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Nonclinical & Early Development Services

Optimize early drug development studies and decisions with our partner labs for First-in-Rodent®, in vitro ADME assays, and Model Informed Drug Development. We partner with our clients to help with candidate selection, dose prediction PK/PD, and Pre-IND readiness and transitions to early clinical development.

    • CANDIDATE SELECTION

    • SINGLE / MULTIPLE DOSE STUDIES

    • PHAMRACOLOGY

    • BEHAVIORAL MODELS

    • MODEL INFORMED DRUG DEVELOPMENT (MIDD)

    • PRE-IND READINESS

    • BLINDED PROPOSALS FROM MOST SUITABLE LABS AND CRUs

    • ONSITE VISITS / AUDITS

    • PARTNER WITH CLIENT ON SELECTION

    • GLP & NONGLP TK ANALYSIS

    • PK & PD ANALYSIS

    • MODEL INFORMED DRUG DEVELOPMENT (MIDD)

SYNAPTIGEN partners with Xyzagen’s nonclinical wet lab and rodent vivarium facilities in Pittsboro NC. A part of our mission is to do smarter drug development quickly and efficiently maintaining scientific rigor, data integrity, and maximizing the 3 R’s. We chose this partner for the following reasons:

  • Seasoned team of scientist and molecule champions

  • CMC capabilities

  • Dosing of rodents and sample draws

  • Bioanalytical lab capabilities

  • pharmacokinetic experts

All of these capabilities are under one roof for fast go-no-go decision making at a cost that will not break the bank and the value that the team adds with as an extension of clients scientific teams. They do not just check boxed, they integrate with our project managers and clients to bring the best strategy and insights to your early development needs.

    • GENERAL NONCLINICAL ADME

    • OPTHALMOLOGY

    • NEUROLOGY / PAIN

    • ANTI-INFECTIVES

    • RESPIRATORY